Abstract: Objective To compare the curative effect and postoperative complications of hemorrhoids between lauromacrogol injection and surgical ligation，in order to explore the best method for hemorrhoids.
Methods 93 patients with hemorrhoids were divided into two groups：48 patients received endoscopic sclerotherapy; 45 patients underwent surgical ligation.The clinical efficacy，subjective feelings and postoperative complications between the two groups were compared.
Results 44 cases in the study group completed the study，in which 21 cases cured，11 cases markedly effective，8 cases effective，4 cases ineffective，and the total effective rate was 90.91%.42 cases in the control group were completed the study，in which 23 cases cured，13 cases markedly effective，4 cases effective，2 cases ineffective，and the total effective rate was 95.24%.There was no significant difference in clinical efficacy and total effective rate between the two groups（P>0.05）.Before and after treatment，there was no significant difference in European quality of life-5 dimensions，5-level（EQ-5D-5L）and Vaizey scores between the two groups（P>0.05）.The incidence of postoperative adverse reactions in the study group was lower than that in the control group（9.09% vs 28.57%，P<0.05）.
Conclusion Sclerotherapy is equivalent to hemorrhoidectomy in short-term efficacy，but has fewer postoperative complications.

Key words: hemorrhoids, lauromacrogol, sclerotherapy, hemorrhoidectomy, efficacy, complication