Abstract: Objective:To evaluate the sidetoside isoperistaltic anastomosis and functional endtoend anastomosis in digestive tract reconstruction of Crohn's disease.Methods:Clinical and followup data of CD patients who underwent intestinal resection from March 2017 to October 2019 were retrospectively analyzed.Result:Seventytwo CD patients underwent bowel anastomosis 78 times，in which sidetoside isoperistaltic anastomosis（SSIA）63 times（small intestinesmall intestine 44 times，small intestinecolon 10 times，and the coloncolon 9 times），and functional endtoend anastomosis（FEEA）15 times（small intestinethe small intestine 4 times，small intestinecolon 7 times，and coloncolon 4 times）.Anastomotic proximal enterostomy occured in 7 cases.SSIA completion time was（32±14）min，and FEEA completion time（19±6）min.The postoperative hospitalization time of patients receiving SSIA was 7～14 days（mean 9.1 days）.Patients receiving FEEA were hospitalized for 8～15 days（mean 8.7 days）.One patient receiving FEEA and proximal stoma developed anastomotic leakage.There was no anastomotic stenosis in those two anastomotic methods.Conclusion:Both SSIA and FEEA are suitable for gastrointestinal reconstruction after CD intestinal resection.However，SSIA may be preferred for mesenteric hypertrophy or anastomosis of the transverse and left hemicolon.

Key words: Crohn's disease, 〓sidetoside isoperistaltic anastomosis, 〓functional endtoend anastomosis, 〓complications