Abstract: Objective To study the application value of the supraclavicular and anterior sternocleidomastoid space approach in open thyroid cancer surgery.Methods A retrospective study of 65 patients with thyroid cancer from January 2023 to December 2023 was conducted,the patients were divided into experimental group (30 cases) and control group (35 cases),which received thyroid cancer operation via supraclavicular and Sternocleidomastoid muscle anterior space approach and conventional open thyroid cancer operation respectively.The perioperative period,quality of life,pain and complications were compared between the two groups.Results The incision length, the number of lymph nodes removed, the operation time, the blood loss, the drainage volume, the drainage time and the hospital stay in the observation group were (4.00±0.76) cm, (6.41±0.73), (66.32±2.93) minutes, (37.14±6.69) mL, (1.41±0.59) days and (16.68±1.9), respectively 1) ml and (5.14±1.25) days.The control groups were (5.54±1.03) cm, (4.31±0.68) pieces, (80.42±2.96) minutes, (55.54±2.67) ml, (3.15±0.67) days, (31.19±1.96) ml and (7.88±1.28) days respectively. There was a statistically significant difference between the two groups (P<0.001).Under the effects of interaction, time point effect and inter-group effect, the EQ-5D-5L scale and NRS score will change with the time point variation due to different surgical methods. The incidences of choking cough when drinking water, neck tightness sensation and total adverse events in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.001).Conclusion The supraclavicular and anterior sternocleidomastoid approach can reduce the length of incision,shorten the operation time,reduce postoperative pain and complications,and improve the quality of life of patients with thyroid cancer.

Key words: transclavicular supraclavicular, anterior sternocleidomastoid space approach, openness, thyroid cancer