Abstract: Hepatocellular carcinoma and intrahepatic cholangiocarcinoma collision tumors are clinically rare and lack specific imaging features,making them prone to misdiagnosis.This article reports a case of a 42-year-old female patient diagnosed with a hepatic collision tumor through surgical pathology,with immunohistochemistry confirming the independent existence of the two carcinoma components.The pathogenesis,diagnosis,and differential diagnosis are discussed with reference to literature,aiming to improve understanding of this disease and reduce the rate of clinical misdiagnosis.

Key words: hepatic collision tumor, hepatocellular carcinoma, intrahepatic cholangiocarcinoma