Abstract: Objective To evaluate the predictive value of preoperative hemoglobin,albumin,lymphocyte,and platelet (HALP) scores for postoperative complications following laparoscopic cholecystectomy in patients with acute cholecystitis (AC).Methods A total of 160 patients with acute cholecystitis  AC who underwent laparoscopic cholecystectomy from May 2021 to May 2024 were selected as the research subjects.The preoperative HALP scores of AC patients with different disease severity and postoperative complications were compared to analyze the predictive value of preoperative HALP scores for postoperative complications in AC patients.The relationship between  preoperative HALP scores and the occurrence of postoperative complications in AC patients was analyzed.The independent correlation between postoperative complications in AC patients and preoperative HALP scores was also analyzed.Results As the condition worsened,the preoperative HALP score gradually decreased.(P<0.001);the preoperative HALP score of patients with poor prognosis in AC was significantly lower than that of patients with good prognosis (P<0.001);the preoperative HALP score had a high predictive value for the occurrence of postoperative complications in AC patients (P<0.001);a low preoperative HALP score was an independent risk factor for postoperative complications in AC patients.Conclusion The reduction in preoperative HALP score is closely related to disease progression and postoperative complications of AC patients.Moreover,the preoperative HALP score can effectively predict the occurrence of postoperative complications in AC patients,and it holds significant clinical importance for the prognosis assessment and reatment  of AC patients.

Key words: hemoglobin, albumin, lymphocyte, and platelet score;acute cholecystitis;laparoscopic cholecystectomy;complications;prognosis