Abstract: Objective：To investigate the sexual function of patients with nonmuscle invasive bladder cancer during intravesical treatment,and analyze possible influencing factors.Method：A total of 198 patients with nonmuscle invasive bladder cancer were enrolled.After transurethral resection of bladder tumors,patients who underwent intravesical treatment.The European Organisation for Research and Treatment of CancerNonMuscleInvasiv Bladder Cancer Quality of Life Questionnaire(EORTC QLQNMIBC24),the Female Sexual Function Index(FSFI) for female,the national Sexual Function Index(IIEF5) for male,Evaluation Scale for Communication with Spouse about cancerrelated concerns was used to obtained data to analyze the status of sexual function in patients with nonmuscle invasive bladder cancer during intravesical treatment.Result：84 patients stopped sexual activity during intravesical treatment,114 patients with sexual life have a lower frequency of sexual life than before intravesical treatment.86.51% of men and 88.00% of women have different degrees of sexual dysfunction.During intravesical treatment,the patients had different degrees of lower urinary tract symptoms(21.27±9.67).Patients who stop sex life have severe lower urinary tract symptoms.47% of patients worry that sexual activity will “contaminating” each other.Regarding sex life,7.5% of patients received medical staff guidance during intravesical treatment.Compared with patients with sexual life,patients who stopped sexual life had lower scores for sexual function and sexual communication with their spouses(0.69±0.55 vs 1.75±1.08).Conclusion：The sexual function of patients with nonmuscle invasive bladder cancer is negatively affected during intravesical treatment, Clinical staff should inform patients about the impact of related treatment on sexual function before intravesical treatment,,eliminate the “contamination” of sexual life and affect disease rehabilitation Misunderstanding,encourage couples to communicate about sexual life issues in order to improve the quality of sexual life of patients.

Key words: nonmuscleinvasive bladder cancer, intravesical treatment, sexual function, sex life instruction, partner communication