Abstract: Objective：To investigate the impact of warmed and humidified carbon dioxide on patients undergoing laparoscopic general surgery.Methods：152 patients undergoing laparoscopic general surgery were randomly divided into two groups（n=76）：Group WH（Wet &Heat）received warmed（37℃）and humidified（98%RH）insufflation carbon dioxide.Group CD received unprocessed carbon dioxide.Operation duration，awakening time were recorded.Body temperature was measured postpneumoperitoneum 30 mins，60 mins，90 mins.Blood coagulation value and pH were observed before surgery and 60 mins after pneumoperitoneum.Results：The operation duration was no difference between two groups.Awakening time of Group WH was shorter than Group CD（P＜0.05）.Body temperature decline after pneumoperitoneum in Group CD Group WH were lower than Group WH after pneumoperitoneum in 60 and 90 mins（P＜0.05）.The two groups of patients showed no significant difference in coagulation value（P＞0.05）.And the pH value of Group CD was lower than Group WH.Conclusion：Heating and humidifying the carbon dioxide gas can better maintain the temperature of patients in the perioperative.

Key words: general surgical procedure；laparoscopy；pneumoperitoneum；carbon dioxide