Abstract: Objective To investigate the feasibility，and safety of laparoscopic resection for colorectal tumor by natural orifice specimen extraction surgery（NOSES）for lcolorectal tumor.
Methods The Clinical data of 68 patients with colorectal tumor Accord with NOSE were retrospectively analyzed，including30 cases of NOSES and 38 cases of traditional laparoscopic.The operation time，intraoperative blood loss，postoperative intestinal function recovery，hospitalization time，postoperative pathological indexes and postoperative complications were observed and recorded in the two groups.
Results There were no significant difference  in age，gender，tumor stage，Tumor diameter，time of operation，biood loss，and postoperative complications between the two groups（P＞0.05）.The recovery of intestinal function and hospitalization time in NOSES operation group were significantly better than those in traditional operation group（P＜0.05）.
Conclusions NOSES is safe and feasible for the patients with laparoscopic resection for colorectal tumor，the patients can recover early and incision is showed more cosmetic，and without increasing complication incidence．

Key words: laparoscopy, colorectal tumor, natural orifice specimen extraction surgery