临床外科杂志 ›› 2018, Vol. 26 ›› Issue (12): 936-939.doi: 10.3969/j.issn.10056483.2018.12.014

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胰腺良性与交界性肿瘤:胰腺中段切除术与胰体尾切除术的临床疗效对比分析

  

  1. 青岛大学附属医院肝胆胰外科
  • 出版日期:2018-12-20 发布日期:2018-12-20

Benign or low grade malignant pancreatic lesions:comparison analysis of clinical efficacy in central pancreatectomy versus distal pancreatectomy

  • Online:2018-12-20 Published:2018-12-20

摘要: [摘要]目的:分析胰腺中段切除术(CP)与胰体尾切除术(DP)在治疗胰腺良性与交界性肿瘤中的临床疗效差异。方法:采用回顾性描述性研究方法,收集分析我院39例CP与52例DP的病例。观察病人的基本临床特征与术中情况、术后并发症和随访情况。结果:CP组的手术时间为(220.96±90.69)分钟,术后进食时间为(4.29±1.05)天;DP组手术时间为(275.52±88.78)分钟,术后进食时间为(5.28±2.22)天,两组比较差异具有统计学意义(P<0.05)。胰瘘(B+C)、延迟性胃排空障碍、二次手术和死亡率等严重并发症中,两组比较未出现显著差异(P>0.05)。与DP组相比,CP组病人在内、外分泌胰腺功能的保存中占明显优势,差异具有统计学意义(P<0.05)。结论:对于位于胰腺颈体部良性肿瘤和低度恶性肿瘤,CP是一种有效的治疗方法。相较于DP,行CP病人能够更好的从术后胰腺的内、外分泌功能保留中获益。

关键词: 胰腺肿瘤, 胰腺中段切除术, 胰体尾切除术, 内分泌功能, 外分泌功能

Abstract: [Abstract]〓Objective〖WTBZ〗〓To analyze differences in clinical efficacy of central pancreatectomy(CP)and distal pancreatectomy(DP)in the treatment of benign or borderline tumors of the pancreas.〖WTHZ〗Method〖WTBZ〗〓A retrospective study was used to analyze 39 cases of central pancreatectomy(CP group)and 52 cases of distal pancreatectomy(DP group).The basic clinical features,intraoperative condition,postoperative complications and follow-up of the patients were observed.〖WTHZ〗Result〖WTBZ〗〓In the CP group,the operation time[(220.96±90.69)min] and diet start time[(4.29±1.05)d] were significantly longer than DP group[(275.52±88.78)min and(5.28±2.22)d](P<0.05).There was no significant difference in serious complications including clinically significant pancreatic fistula(B+C),delayed gastric emptying,reoperative,and mortality(P>0.05).Compared with DP group,CP group patients could benefit from longterm postoperative exocrine and endocrine function(P<0.05).〖WTHZ〗Conclusion〖WTBZ〗〓These findings provide a rationale for CP could as an acceptable and reliable procedure,especially in improving the quality of life of patients.

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