腹腔镜微创手术治疗急性胆囊炎病人的炎性因子含量、临床疗效及安全性的观察

doi:10.3969/j.issn.1005-6483.2020.04.016

摘要/Abstract

摘要： 目的比较腹腔镜微创手术治疗急性胆囊炎病人的炎性因子含量、临床疗效及安全性。方法 2015年1月～2019年1月我院收治的急性胆囊炎病人100例。按手术方式分为两组，每组各50例。对照组采用传统开腹胆囊切除手术，观察组采用腹腔镜微创手术。治疗后，记录病人的各项临床指标并统计治疗效果。结果观察组住院时间、术中出血量、手术时间、胃肠功能恢复及下床活动时间均低于对照组，差异有统计学意义（P＜0.05）。术后1天及术后7天，观察组的肿瘤坏死因子α、白细胞介素及C反应蛋白低于对照组，差异有统计学意义（P＜0.05）。两组有效率及并发症发生率比较，差异有统计学意义（P＜0.05）。结论腹腔境胆囊切除术创伤小、术中出血量少，术后肠道功能恢复快，能有效降低炎性反应，提高治疗效果。

关键词: 腹腔镜, 微创手术, 急性胆囊炎, 炎性因子

Abstract: Objective To compare the content，clinical efficacy and safety of inflammatory factors in patients with acute cholecystitis treated by laparoscopic minimally invasive surgery. Methods 100 patients with acute cholecystitis admitted to our hospital from January 2015 to January 2019 were randomly selected as the study subjects.The control group was treated with traditional open cholecystectomy，while the observation group was treated with laparoscopic minimally invasive surgery.After treatment，the clinical indicators of the patients were recorded and the therapeutic effect of the patients was counted. Results The hospitalization time，intraoperative bleeding volume，operation time，recovery of gastrointestinal function and time of getting out of bed in the observation group were significantly lower than those in the control group（P<0.05）.One day after operation and seven days after operation，there were significant differences in TNF-alpha，interleukin and C-reactive protein between the observation group and the control group（P<0.05）.There were significant differences in the effective rate and the incidence of complications between the observation group and the control group（P<0.05）. Conclusion Cholecystectomy in abdominal cavity has the advantages of less trauma，less intraoperative bleeding and fast recovery of intestinal function，which can effectively reduce inflammatory response and improve the treatment effect.The operation scheme is worthy of clinical application.

Key words: laparoscopy, minimally invasive surgery, acute cholecystitis, inflammatory factors

梁勇廖波万波李春林. 腹腔镜微创手术治疗急性胆囊炎病人的炎性因子含量、临床疗效及安全性的观察[J]. 临床外科杂志, 2020, 28(4): 350-352.

LIANG Yong, LIAO Bo, WAN Bo, et al.. The clinical efficacy and safety of laparoscopic minimally invasive surgery for acute cholecystitis[J]. JOURNAL OF CLINICAL SURGERY, 2020, 28(4): 350-352.

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