Abstract: Objective To investigate the diagnosis and treatment of adult inguinal hernia by totally extraperitoneal  prosthesis（TEP）under laparoscopy.
MethodsA retrospective analysis was performed on 1021 cases of TEP in our hospital from May 2014 to May 2019，and the correlation between operation time，the incidence of seroma and general clinical data was compared and analyzed to summarize clinical experience.
ResultsIn this group，1021 patients underwent TEP，and no patients were transferred to open surgery.The average operative time（37.93±16.14）min，the average intraoperative blood loss（3.55±3.02）ml，the average postoperative drainage volume（75.44±53.11）ml，the average postoperative hospital stay（4.25±0.86）days.There were 12 cases of seroma，3 cases of testicular pain，2 cases of umbilical incision infection，and no patch infection，hernia recurrence，testicular atrophy or chronic pain.The operation time of bilateral hernia was longer than that of unilateral hernia，and the difference was statistically significant（P<0.05）.The operation time of indirect hernia was longer than that of direct hernia，and the difference was statistically significant（P<0.05）.The operation time of scrotal hernia was longer than that of non-scrotal hernia，and the difference was statistically significant（P<0.05）.The incidence of seroma after scrotal hernia was higher than that of non-scrotal hernia，and the difference was statistically significant（P<0.05）.
Conclusion Scrotal hernia is an important factor that increases the difficulty of TEP operation and is an independent risk factor for seroma after TEP operation.

Key words: laparoscopic, total extraperitoneal, inguinal Hernia