Abstract:   Objective     The purpose of this study was to examine the effect of clinical pathway of rehabilitation on perioperative VTE in older patients with THA of hip fractures.   Methods  139 older patients with THA of hip fractures were randomly divided into the conventional therapy group and the rehabilitation clinical pathway group.Conventional therapy group（n=75）receive conventional exercise therapy to preventing thrombosis.Rehabilitation clinical pathway group（n=64）receive motility rehabilitation therapy on admission.Ddimer level and whole blood viscosity were compared when the treatment is over.Moreover，the risks of bleeding and the morbidity of deep vein thrombosis（DVT）and pulmonary embolism（PE）after surgery were evaluated.  Results  Compared with conventional therapy group[（326.11±93.05）μg/L and（4.42±0.65）mPa〖DK〗·s]，Ddimer level[（300.25±90.28）μg/L] and whole blood viscosity[（3.33±0.45）mPa〖DK〗·s] in rehabilitation clinical pathway group were significantly decreased（P＜0.05）.The incidence of DVT within one month after surgery in the clinical pathway of rehabilitation group was significantly lower（10.9%）than in the conventional group（25.3%）（P＜0.05）.There was no significant difference in PE incidence between the two groups（P＞0.05）.  Conclusion  Clinical pathway of rehabilitation combined with anticoagulant drugs can significantly reduce the risk of VTE with in 1 month after the THA of hip fractures in highrisk population over 65 years of age.

Key words:  ,  , tatol hip arthroplasty, clinical pathway of rehabilitation, Anticoagulant, venous thromboembolism