JOURNAL OF CLINICAL SURGERY ›› 2019, Vol. 27 ›› Issue (11): 968-971.doi: 10.3969/j.issn.1005-6483.2019.11.014

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Single kidney transplantation from small pediatric donors younger than 3 years into adult recipients:39 cases reports

  

  • Online:2019-11-20 Published:2019-11-20

Abstract: Objective:To summariz the outcome of single kidney transplantation(SKT)from infant donors to adult recipients.Methods:From 2014 to 2016,thirtynine adults receiving SKT from deceased small pediatric donors younger than 3 years old were enrolled and analyzed retrospectively.The recipients were divided into infant donor group(≤1 year age,n=9)and young children group(1<age<3 years,n=30).The incidence of complications and delayed graft function(DGF),patient and graft survival outcomes,serum creatinine level(SCr)were recorded and analyzed.Results:All patients recovered without graft loss due to surgical complications.Two patients in infant donor group died of pneumonia in the first 6 months postoperation.In young children group,one patient died of pneumonia,another died of unknown reason.Deathcensored graft survival were 100% in both groups.There were no significant differences in the incidence of DGF(44.4% vs.26.7%,P>0.05)and the mean SCr at 12month followup [(74.14±18.52)μmol/L vs.(91.46±26.91)μmol/L,P>0.05)].Moreover,the incidence of proteinuria showed no significant difference(33.3% vs.36.7%,P>0.05).Conclusion:SKT from deceased infant donors could be transplanted into adults with moderate graft function and favorable graft survival outcome.Increased incidence of earlyphase proteinuria may be associated with inadequate size of kidney grafts and hyperperfusion injury.

Key words: pediatric, donor, kidney, transplantation

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