Abstract: ObjectiveThis study aimed to evaluate clinical effects and related issues of subdermal excision of apocrine glands through small incisions for axillary osmidrosis.Methods From March 2016 to February 2018，42 cases of moderate-to-severe axillary osmidrosis were treated with subdermal excision of apocrine glands through small incisions along underarm creases.Follow-up was performed in 1，3，6 months.Results All 42 cases were followed up for an average of 5 months.In 2 cases（3 sides），the incision was not well healed.The maximum area of the wound was about 1×1.5 cm， which was healed after dressing and debridement.The rest were all healed naturally.At follow-up，3 males and 1 female relapsed with unilateral subgingival odor，which was mild; no hematoma，flap necrosis and nerve injury occurred.Conclusion After subdermal excision of apocrine glands for axillary osmidrosis，the incision along underarm creases was concealed，the wound was relatively small，and the treatment was thorough.The postoperative scar was small and concealed，and the effect was satisfactory.

Key words: axillary osmidrosis, small incision, apocrine glands removal, minimally invasive