临床外科杂志 ›› 2022, Vol. 30 ›› Issue (2): 171-174.doi: 10.3969/j.issn.1005-6483.2022.02.022

• 论著 • 上一篇    下一篇

腹腔镜辅助胃癌根治术后并发症的Clavien-Dindo分级及影响因素分析

  

  1. 351100 福建省莆田学院附属医院胃肠外二科
  • 收稿日期:2021-04-04 接受日期:2021-04-04 出版日期:2022-02-20 发布日期:2022-02-20
  • 通讯作者: 林铭,Email:cmfjmu@163.com

Analysis of Clavien-Dindo classification of complications and impact factors after laparoscopic assisted radical gastrectomy for gastric cancer

  1. Department of Gastrointestinal Surgery,Affiliated Hospital of Putian University,Fujian,Putian 351100,China
  • Received:2021-04-04 Accepted:2021-04-04 Online:2022-02-20 Published:2022-02-20

摘要:  目的 探讨腹腔镜辅助胃癌根治术后并发症的Clavien-Dindo分级情况及影响因素。 方法 2014年1月~2019年6月间行腹腔镜辅助胃癌根治术病人478例,根据Clavien-Dindo分级系统分析术后并发症的发生情况,采用Logistic回归分析术后并发症发生的影响因素。 结果 478例病人出现术后并发症84例(17.6%),并发症Clavien-Dindo分级Ⅰ级 6例,Ⅱ级 59例,Ⅲa级 11例,Ⅲb级 4例,Ⅳa级 3例,Ⅴ级 1例。Logistic单因素分析结果显示,病人年龄、体质指数(BMI)、术前合并症、手术时间、术中出血量、肿瘤直径、围手术期输血与术后并发症发生有关(P<0.05)。多因素分析表明,年龄≥65岁(OR=2.251,P=0.002)、BMI≥28kg/m2(OR=2.970,P=0.019)、手术时间>180分钟(OR=1.771,P=0.035)、术中出血量≥200ml(OR=1.825,P=0.045)和围手术期输血(OR=1.990,P=0.045)是腹腔镜辅助胃癌根治术后并发症发生的独立危险因素(P<0.05)。年龄、BMI、手术时间、术中出血量及围手术期输血的并发症Clavien-Dindo分级结果差异均有统计学意义(P<0.05)。结论 腹腔镜辅助胃癌根治术后并发症应用Clavien-Dindo分级可对手术的安全性进行评估,常见并发症为Clavien-Dindo分级Ⅱ级,病人年龄、BMI、手术时间、术中出血量及围手术期输血是术后并发症发生独立危险因素。

关键词: 胃肿瘤, 腹腔镜, Clavien-Dindo分级, 并发症

Abstract: Objective To investigate the Clavien-Dindo classification of complications after laparoscopic-assisted radical gastrectomy and the impact factors.Methods Clinical data of 478 patients with gastric cancer undergoing laparoscopic-assisted radical resection from January 2014 to June 2019 were analyzed retrospectively.The postoperative complications were assessed by Clavien-Dindo classification,and the impact factors associated with postoperative complications were assessed by using the Logistic regression model. Results Of the 478 patients,postoperative complications occurred in 84 patients(17.6%).The Clavien-Dindo classification of postoperative complication:6 patients were detected in gradeⅠ,59 in gradeⅡ,11 in grade Ⅲa,4 in grade Ⅲb,3 in grade Ⅳa and 1 in grade Ⅴ,respectively.On univariate logistic analysis,postoperative complication was associated with age,BMI,preoperative comorbidity,surgical duration,intraoperative blood loss,tumor size and perioperative transfusion.Multivariate analysis revealed that age age≥65 years,BMI≥28kg/m2,surgical duration time>180min,intraoperative blood loss≥200ml and perioperative transfusion were independent risk factors for postoperative complications.The grades of Clavien-Dindo classification were significantly different between patients with different age,BMI,surgical duration,intraoperative blood loss and perioperative transfusion(all P<0.05).Conclusion Clavien-Dindo classification of complicationsis beneficial to the comprehensive evaluation of safety of laparoscopic-assisted radical gastrectomy.The mainly complications after laparoscopic-assisted radical gastrectomy are grade Ⅱ of Clavien-Dindo classifification.Age,BMI,surgical duration,intraoperative blood loss and perioperative transfusion were independent risk factors for postoperative complications in laparoscopic-assisted radical gastrectomy.

Key words: stomach neoplasms, laparoscopic surgical procedures, Clavien-Dindo classification, postoperative complication

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