ω-3鱼油脂肪乳对腹腔镜辅助胃癌根治术后影响的研究

doi:10.3969/j.issn.1005-6483.2021.09.016

摘要/Abstract

摘要： 目的探讨ω-鱼油脂肪乳对腹腔镜辅助胃癌根术后临床结局的影响。
方法 2018年2月～2019年10月期间我院胃肠外科行腹腔镜辅助胃癌根治术的病人80例，电脑随机分为研究组和对照组。研究组从术后第1天开始在肠外营养中添加10%的鱼油脂肪乳剂100ml；对照组术后采取常规治疗措施。比较两组术后恢复指标、术后肠内营养实际鼻饲量及相关并发症、术后手术相关并发症的发生情况。
结果共计80例病人完成研究，研究组40例，对照组40例。两组病人术后首次通气时间、术后首次排便时间、术后住院时间及住院总费用比较差异均无统计学意义(P＞0.05)。研究组术后4天、术后5天及术后6天实际肠内营养鼻饲量均大于对照组，差异有统计学意义(均P<0.05)；研究组恶心和腹胀发生率[17.5%(7/40)和37.5%(15/40)]均低于对照组[27.5%(11/40)和70.0%(28/40)]，两组比较，差异均具有统计学意义(P<0.05)。研究组感染性并发症发生率低于对照组，两组比较，差异有统计学意义(P<0.05)；研究组非感染性并发症发生率与对照组比较，差异无统计学意义(P＞0.05)。
结论腹腔镜辅助胃癌根治术后使用鱼油脂肪乳可以提高肠内营养的耐受性，降低术后感染性并发症的发生率。

关键词: ω-3鱼油脂肪乳, 胃肿瘤, 胃癌, 胃切除术, 腹腔镜

Abstract: Objective To investigate the effect of fish oil fat emulsion on clinical outcome of laparoscopic assisted radical operation for gastric cancer.
Methods From June 2018 to September 2019,undergoing laparoscopic assisted radical resection of gastric cancer patients were randomly divided into experimental group and control group.From the first day after operation,10% fish oil fat emulsion 100 mL was added to parenteral nutrition in the experimental group,and the patients in the control group were treated with routine treatment after operation.The occurrence of postoperative recovery index,the actual nasal feeding volume of postoperative intestinal nutrition and related complications,and the complications related to postoperative surgery were compared.
Results A total of 80 patients completed the study.There were 40 cases in the experimental group and 40 cases in the control group.There was no statistical difference in the first ventilation time,the first defecation time,the postoperative hospitalization time and the total hospitalization cost between the two groups(P＞0.05).On the 4st,5rd and 6th day after operation,the actual amount of enteral nutrition nasal feeding in the experimental group was higher than that in the control group,the difference was statistically significant(all P<0.05);compared with the control group,the incidence of nausea [17.5%(7/40) and 37.5%(15/40)],abdominal distension were lower [27.5%(11/40) and 70.0%(28/40)],the differences were statistically significant(all P<0.05).The incidence of total infectious complications in the experimental group was significantly lower than that in the control group(P<0.05),but there was no significant difference in the incidence of total non-infectious complications between the experimental group and the control group(P>0.05).
Conclusion Using fish oil fat emulsion after laparoscopic assisted radical resection of gastric cancer can improve tolerance to enteral nutrition,and reduce the occurrence of postoperative total infectious complications.

Key words: ω-3 fish oil fat emulsion, gastric tumor, gastric cancer, gastectomy, laparoscopy

程康文马冬花孙陟王亚娟王洁左贵泽王贵和. ω-3鱼油脂肪乳对腹腔镜辅助胃癌根治术后影响的研究[J]. 临床外科杂志, 2021, 29(9): 853-856.

CHENG Kangwen, MA Donghua, SUN Zhi, et al.. Effect of omega-3 fish oil fat emulsion on laparoscopic assisted radical operation for gastric cancer[J]. JOURNAL OF CLINICAL SURGERY, 2021, 29(9): 853-856.

参考文献

相关文章 15

[1]	桑庆王亮张能维. 腹腔镜下胃旁路术在减重与代谢外科的应用进展[J]. 临床外科杂志, 2021, 29(9): 805-808.
[2]	杨珵璨戴谦诚王兵. 腹腔镜胃袖状切除联合单吻合口十二指肠回肠旁路术手术相关问题及研究进展[J]. 临床外科杂志, 2021, 29(9): 809-811.
[3]	刘家盛罗建飞. 袖状胃切除复合手术的应用进展[J]. 临床外科杂志, 2021, 29(9): 812-815.
[4]	明炜吕建发刘高利侯国强胡海峰龙杏林张文涵谢颂平. 胸腔镜下全食管系膜切除术在食管癌根治术中的应用分析[J]. 临床外科杂志, 2021, 29(9): 827-829.
[5]	王海霖段光辉田运刘宏斌. 肠镜下治疗阑尾术后盲肠-腹壁瘘一例[J]. 临床外科杂志, 2021, 29(9): 846-847.
[6]	胡欣雨姚晖夏冬 Sami UL Haq Niazi. 鸟嘌呤核苷酸交换因子在胃癌组织中的表达及其临床意义[J]. 临床外科杂志, 2021, 29(9): 848-852.
[7]	金曜汪翰杨帆陶凯雄张弦. 腹腔镜技术在嵌顿性腹股沟疝中的应用[J]. 临床外科杂志, 2021, 29(9): 857-859.
[8]	张金梅颉玙张敏雷霆. 胃大部切除毕Ⅱ式吻合术后并发Petersen疝一例[J]. 临床外科杂志, 2021, 29(9): 900-900.
[9]	尹露, 王恒, 王健等. 腹腔镜胆囊切除术中发生二氧化碳气栓的麻醉处理一例[J]. 临床外科杂志, 2021, 29(8): 720-721.
[10]	李翔, 齐涵, 李玉文等. 两种切除术对胃癌病人术后康复及外周血细胞表面PDL1表达的影响[J]. 临床外科杂志, 2021, 29(8): 754-756.
[11]	徐盟秦仁义. 腹腔镜胰腺手术器官保留的技巧和运用[J]. 临床外科杂志, 2021, 29(7): 604-606.
[12]	郑元文刘军. 腹腔镜胰十二指肠切除术中胆肠吻合的回顾与探讨[J]. 临床外科杂志, 2021, 29(7): 607-609.
[13]	黄小兵. 胰腺微创手术获益人群探讨[J]. 临床外科杂志, 2021, 29(7): 610-612.
[14]	刘建华. 胰腺微创手术术中、术后严重并发症的预防和处理[J]. 临床外科杂志, 2021, 29(7): 613-615.
[15]	刘亚辉. 胰腺微创手术中胰腺残端处理[J]. 临床外科杂志, 2021, 29(7): 616-618.

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed

本文评价

推荐阅读 10

[1]	陈国骥杨华王存川. 减重手术在代谢外科中的应用及疗效[J]. 临床外科杂志, 2021, 29(9): 801 -804 .
[2]	桑庆王亮张能维. 腹腔镜下胃旁路术在减重与代谢外科的应用进展[J]. 临床外科杂志, 2021, 29(9): 805 -808 .
[3]	杨珵璨戴谦诚王兵. 腹腔镜胃袖状切除联合单吻合口十二指肠回肠旁路术手术相关问题及研究进展[J]. 临床外科杂志, 2021, 29(9): 809 -811 .
[4]	刘家盛罗建飞. 袖状胃切除复合手术的应用进展[J]. 临床外科杂志, 2021, 29(9): 812 -815 .
[5]	梁辉李聪. 减重代谢外科术后随访的挑战与对策[J]. 临床外科杂志, 2021, 29(9): 815 -817 .
[6]	白洁陶凯雄. 肥胖病人胃旁路术后并发症的防治研究进展[J]. 临床外科杂志, 2021, 29(9): 818 -820 .
[7]	江竟成张超王瀚邓青山吴蛟罗鹏邱俊周世军陶裕川徐小平屈小琴向玉易勇. 自体颅骨修补术术前颅骨处理方式对修复效果的影响[J]. 临床外科杂志, 2021, 29(9): 821 -823 .
[8]	付敏向少伟吴洪崔显念李松. 降钙素原、C反应蛋白、肿瘤坏死因子-α、白介素-6及肝素结合蛋白联合检测在颅内感染病原鉴别诊断中的作用[J]. 临床外科杂志, 2021, 29(9): 824 -826 .
[9]	明炜吕建发刘高利侯国强胡海峰龙杏林张文涵谢颂平. 胸腔镜下全食管系膜切除术在食管癌根治术中的应用分析[J]. 临床外科杂志, 2021, 29(9): 827 -829 .
[10]	刘晓军韩笑王盼李建华蓝新颜. 3D-CT影像技术在胸腔镜肺手术中的应用[J]. 临床外科杂志, 2021, 29(9): 830 -833 .