三维打印技术辅助设计股前外侧穿支皮瓣联合负压封闭引流治疗手或足复合组织缺损的临床效果观察

doi:10.3969/j.issn.1005-6483.20250052

临床外科杂志 ›› 2026, Vol. 34 ›› Issue (5): 585-588.doi: 10.3969/j.issn.1005-6483.20250052

三维打印技术辅助设计股前外侧穿支皮瓣联合负压封闭引流治疗手或足复合组织缺损的临床效果观察

261000 山东潍坊，陆军第八十集团军医院骨科（安宝鑫、张永超、孙健、曲新强），麻醉科（杨淑怡）

收稿日期:2025-01-03 修回日期:2025-01-03 出版日期:2026-05-20 发布日期:2026-05-20
通讯作者: 曲新强,Email:exaw55@163.com

Observation of clinical efficacy of combined application of 3D printing assisted anterolateral thigh perforator flap and vacuum sealing drainage in treating hand or foot compound tissue defects

Department of Orthopedics,the 80th Group Army Hospital of the People's Liberation Army,Shandong,Weifang 261000，China

Received:2025-01-03 Revised:2025-01-03 Online:2026-05-20 Published:2026-05-20

摘要/Abstract

摘要： 目的研究三维打印技术辅助设计的股前外侧穿支皮瓣与负压封闭引流（VSD）联合应用治疗手部或足部复合组织缺损的临床疗效。方法2021年1月～2024年1月收治的手部或足部复合组织缺损病人104例，采用随机数字表法将其分为对照组和研究组，每组各52例。两组病人均在进行VSD治疗的基础上进行股前外侧穿支皮瓣修复术，对照组对缺损区域进行测量设计皮瓣，研究组采用三维打印技术辅助设计皮瓣。术后对病人的临床疗效、手或足功能[Michigan手功能评价量表（MHQ）、美国矫形足踝外科协会（AOFAS）、炎性因子水平[肿瘤坏死因子（TNF）-α、白细胞介素（IL）-8、IL-6]以及术后并发症进行分析。结果对照组和研究组病人的临床疗效显著优于对照组，对照组和研究组的换药次数分别为（7.68±1.94）次和（ 3.47±0.75）次，抗菌药物应用时间分别为（10.54±2.87 ）天和（ 6.24±1.74）天，创面愈合时间分别为（27.64±3.85）天和（19.64±2.91）天，两组比较差异有统计学意义（P<0.05）。术后，对照组和研究组的TNF-α分别为（310.25±32.44 ）ng/ml和（ 257.64±26.87）ng/ml、IL-6分别为（1.07±0.11 ）ng/ml和（ 0.67±0.06）ng/ml，IL-8分别为（0.97±0.09 ）ng/ml和（0.57±0.05）ng/ml，两组比较差异有统计学意义（P<0.05）。对照组和研究组的MHQ评分分别为（66.87±7.71 ）分和（ 75.21±8.54）分，AOFAS评分分别为（74.58±8.57 ）分和（88.31±9.71）分，两组比较差异有统计学意义（P<0.05）。两组术后并发症发生率比较，差异无统计学意义（P>0.05）。结论应用三维打印技术辅助设计股前外侧穿支皮瓣并与负压封闭引流联合治疗手或足复合组织缺损可以有效的提高病人的临床效果，促进病人的恢复，并减少术后并发症的发生。

关键词: 三维打印技术, 股前外侧穿支皮瓣, 负压封闭引流, 复合组织缺损

Abstract: Objective To investigate the clinical efficacy of combined application of 3D printing assisted anterolateral thigh perforator flap and vacuum sealing drainage (VSD) in treating hand or foot compound tissue defects.Methods A total of 104 patients with hand or foot compound tissue defects admitted to our hospital from January 2021 to January 2024 were regarded as the study sample.They were randomly assigned into control group and research group (52 cases each) via random number table.Both groups underwent anterolateral thigh perforator flap on top of VSD treatment.The control group measured the defect area to design skin flap,while the research group used 3D printing technology to assist in designing the skin flap.After surgery,the efficacy,hand or foot function[Michigan Hand Function Assessment Scale（MHQ）、American orthopedic foot and ankle society（AOFAS）],inflammatory factor levels[Tumor Necrosis Factor-α（TNF-α）、Interleukin-8（IL-8）、Interleukin-6（IL-6）],and postoperative complications were analyzed.Results The research group had unusually better clinical efficacy,and unusually lower dressing changes[（7.68±1.94) vs (3.47±0.75）],duration of antibiotic use[（10.54±2.87)d vs (6.24±1.74）d],and wound healing time[（27.64±3.85)d vs (19.64±2.91）d] than control group (P<0.05).After surgery,research group had unusually lower level of the TNF-α[（310.25±32.44）ng/ml vs (257.64±26.87）ng/ml],IL-6[（1.07±0.11）ng/ml vs (0.67±0.06）ng/ml],and IL-8[（0.97±0.09）ng/ml vs (0.57±0.05）ng/ml],and unusually higher MHQ scores[（66.87±7.71) vs (75.21±8.54）] and AOFAS scores[（74.58±8.57) vs (88.31±9.71）] than the control group (P<0.05).The postoperative complications were not unusually different between the two groups (P>0.05).Conclusion The combined application of 3D printing technology assisted anterolateral thigh perforator flap and VSD can effectively improve the clinical effect of patients with hand or foot compound tissue defects,promote their recovery,and reduce postoperative complications.

Key words: 3D printing technology, anterolateral thigh perforator flap, vacuum sealing drainage, compound tissue defects

安宝鑫张永超杨淑怡孙健曲新强. 三维打印技术辅助设计股前外侧穿支皮瓣联合负压封闭引流治疗手或足复合组织缺损的临床效果观察[J]. 临床外科杂志, 2026, 34(5): 585-588.

AN Baoxin, ZHANG Yongchao, YANG Shuyi, SUN Jian, QU Xinqiang. Observation of clinical efficacy of combined application of 3D printing assisted anterolateral thigh perforator flap and vacuum sealing drainage in treating hand or foot compound tissue defects[J]. JOURNAL OF CLINICAL SURGERY, 2026, 34(5): 585-588.

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三维打印技术辅助设计股前外侧穿支皮瓣联合负压封闭引流治疗手或足复合组织缺损的临床效果观察

Observation of clinical efficacy of combined application of 3D printing assisted anterolateral thigh perforator flap and vacuum sealing drainage in treating hand or foot compound tissue defects

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