关键词: 乳腺癌, 手术, 切口, 愈合不良, 影响因素

Abstract: Objective To analyze the influencing factors of poor incision healing in postoperative patients with breast cancer.Methods The clinical data of 150 patients with breast cancer diagnosed by the Department of Nail Milk surgery of the Fifth affiliated Hospital of Xinjiang Medical University from January 2016 to December 2023 were retrospectively analyzed.According to the postoperative wound healing,the patients were divided into two groups:good healing group (n=94) and poor healing group (n=56).The general data,operation-related data and clinicopathological characteristics of the two groups were collected for univariate analysis,and the single-factor indexes with statistical significance were analyzed by multivariate Logistic analysis to screen the risk factors of poor incision healing after operation.The statistically significant indexes of regression analysis were analyzed by receiver operating characteristic (ROC) curve to further explore its predictive value in poor incision healing after breast cancer operation.Results The data of the two groups were compared and analyzed.Multivariate Logistic regression analysis showed that BMI,diabetes,age,axillary lymph node dissection and hemoglobin were independent risk factors for poor incision healing(P<0.05).ROC curve analysis of independent risk factors showed that when the age was more than 57.5,the area under the curve (AUC) was 0.635,the sensitivity was 55.4%,the specificity was 68.1%,and the critical value was 57.5.When BMI>24.9kg/m²,the area under the curve (AUC) was 0.735,the sensitivity was 87.5%,the specificity was 61.7%,and the critical value was 24.9 (P<0.001).When hemoglobin<101.5g/L,the area under the curve (AUC) was 0.829,the sensitivity was 57.1%,the specificity was 94.7%,and the critical value was 101.5g/L (P<0.001).Conclusion BMI,diabetes,hemoglobin,age and axillary lymph node dissection are independent risk factors for poor wound healing after breast cancer operation.When BMI>24.9kg/m²,age>57.5 years old and hemoglobin<101.5g/L,it can predict the occurrence of poor incision healing in patients with breast cancer.

Key words: breast cancer, surgery, incision, poor healing, influencing factors