临床外科杂志 ›› 2025, Vol. 33 ›› Issue (5): 466-469.doi: 10.3969/j.issn.1005-6483.20250416

• 论著 • 上一篇    下一篇

婴儿肠道手术后胃肠功能障碍的风险因素分析

  

  1. 210008  南京医科大学附属儿童医院新生儿外科
  • 收稿日期:2025-04-18 接受日期:2025-04-18 出版日期:2025-05-20 发布日期:2025-05-20
  • 通讯作者: 唐维兵,Email:twbcn@njmu.edu.cn

Risk factor analysis of postoperative gastrointestinal dysfunction after infant intestinal surgery

  1. Department of Neonatal Surgery,Affiliated Children’s Hospital,Nanjing Medical University,Nanjing 210008,China
  • Received:2025-04-18 Accepted:2025-04-18 Online:2025-05-20 Published:2025-05-20

摘要: 目的  本研究分析婴儿肠道手术后发生(postoperative gastrointestinal dysfunction,POGD)的风险因素。方法 2019年3月~2024年3月我院接受肠吻合手术的围手术期婴儿220例。按术后禁食时间超过5天、呕吐胆汁性液体或鼻胃管引流胆汁性液体、腹胀为标准,根据评判标准分为POGD组(78例)和非POGD组(142例),对两组婴儿临床资料进行单因素分析,将 P<0.05的因素纳入二元Logistics回归分析,分析影响术后胃肠功能恢复的独立影响因素。结果 POGD组与非POGD组术后首次排便时间分别为(1.79±1.78)天和(1.44±0.71)天,肠外营养时间分别为(9.73±4.64)天和(5.19±2.18)天、住院时间分别为(13.31±5.70)天和(8.46±2.90)天,两组比较差异有统计学意义(P<0.05)。多因素回归分析显示,术前年龄别体重Z(weight-forage,WAZ)评分低(P<0.05,OR=0.705)、手术时间长(P<0.05,OR=2.642)是POGD发生的风险因素。结论 术前营养状况差、手术时间长是婴儿发生术后胃肠功能障碍的危险因素。

关键词: postoperative gastrointestinal dysfunction, infants, gastrointestinal function, enhanced recovery after surgery

Abstract: Objective This study analyzes the risk factors for postoperative gastrointestinal dysfunction (POGD) in infants after intestinal surgery.Methods The perioperative clinical data of 220 infants who underwent intestinal surgery in Children’s Hospital of Nanjing Medical University from March 2019 to March 2024 were retrospectively analyzed.Based on the criteria of postoperative “fasting time more than 5d,vomiting bile fluid or bile fluid drainage from nasogastric tube,abdominal distension”,the infants were divided into POGD group(78 cases) and non-POGD group (142 cases),and the clinical data of the two groups were analyzed by one-way analysis,and the independent factors with a P<0.05 were included in the binary Logistic regression analysis to analyze the independent influencing factors affecting the recovery of gastrointestinal function after surgery.Results The time of the first defecation after surgery in the POGD group and the non-POGD group was (1.79±1.78) days and (1.44±0.71) days,respectively,and the time of parenteral nutrition was (9.73±4.64) days and (5.19±2.18) days,respectively,and the hospital stay was (13.31±5.70) days and (8.46±2.90) days,respectively.There was statistically significant difference between the two groups(P < 0.05).Multivariate regression analysis showed that a low preoperative weight for age Z(WAZ) score (P < 0.05,OR= 0.705) and a long operation time (P < 0.05,OR=2.642) were risk factors for POGD.Conclusion Preoperative nutritional status and duration of surgery are risk factors for the development of postoperative gastrointestinal dysfunction in infants.

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