关键词: 颅脑损伤, 胃肠功能障碍, 危险因素, 预后

Abstract: Objective  To analyze the clinical risk factors for gastrointestinal dysfunction in patients with traumatic brain injury.Methods A retrospective analysis was conducted on clinical data of 313 cases of traumatic brain injury in our hospital from January 2022 to October 2023.According to whether gastrointestinal dysfunction occurred at admission,the patients were divided into the occurrence group (Group A,90 cases) and the nonoccurrence group (Group B,223 cases).Multivariate Logistic regression was used to analyze the risk factors of gastrointestinal dysfunction.The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of each factor in predicting gastrointestinal dysfunction in patients with craniocerebral injury.Results Among 313 patients,90 cases (28.75%) experienced gastrointestinal dysfunction.Logistic analysis showed that the admission GCS score was ≤8 points(OR=3.117,95%CI:1.358-7.157,P=0.007),pulmonary infection (OR=7.129,95%CI:1.889-27.377,P=0.004),intracranial infection (OR=3.152,95%CI:1.162-8.548,P=0.024),frontal lobe injury (OR=5.430,95%CI:1.481-19.915,P=0.011),abnormal serum Na levels (OR=8.482,95%CI:1.958-36.247,P=0.004),and decreased Alb (OR=3.001,95%CI:1.137-7.918,P=0.026) and elevated hs CRP (OR=3.142,95%CI:1.159-8.522,P=0.024) were independent risk factors for gastrointestinal dysfunction in patients with traumatic brain injury.The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of each factor in predicting gastrointestinal dysfunction in patients with craniocerebral injury.Conclusion Admission GCS score ≤ 8,pulmonary infection,intracranial infection,frontal lobe injury,abnormal serum Na levels,decreased Alb,and elevated hs CRP are independent risk factors for gastrointestinal dysfunction in patients with traumatic brain injury.

Key words: craniocerebral injury, gastrointestinal dysfunction；risk factors, prognosis