Abstract: Giant colonic duplication (GCD) is a rare congenital malformation associated with significant morbidity, particularly in adult patients, where it can lead to chronic refractory constipation and various complications, imposing a considerable burden on patients and their families.Colonic duplication may lead to various clinical manifestations, and the treatment approaches may differ.This study presents a detailed case report of a 47-year-old female patient with GCD and a 20-year history of refractory constipation, which worsened over the previous month, accompanied by notable abdominal distension and reduced bowel frequency.Clinical evaluation and imaging revealed a markedly dilated colonic segment, contributing to bowel obstruction.The surgical intervention successfully resolved the obstruction, with intraoperative findings indicating a 70 cm segment of the colon terminating at the blind end, highlighting the complexity of this condition.This article primarily focuses on the surgical treatment methods for colonic duplication associated with refractory constipation through a literature review.The study underscores the importance of thorough clinical assessment and imaging in diagnosing GCD, suggesting that early identification may facilitate timely surgical management, thereby improving patient outcomes and quality of life.

Key words: colonic duplication; chronic constipation; intestinal obstruction; subtotal colectomy; surgical management