Abstract: With advances in minimally invasive techniques,non-intubated video-assisted thoracoscopic surgery (NIVATS) is increasingly applied in the treatment of early-stage non-small cell lung cancer (NSCLC).NIVATS preserves the patient's spontaneous breathing,avoiding laryngeal injury,airway edema,and pulmonary complications associated with mechanical ventilation and double-lumen endotracheal intubation,demonstrating significant advantages in postoperative recovery.Studies indicate that NIVATS is particularly suitable for NSCLC patients with good lung function and smaller tumors.However,the application of NIVATS in complex cases remains limited,such as in cases requiring extensive lymph node dissection,tumors close to major blood vessels,and severe pleural adhesions,where patients may need to switch to intubated anesthesia mid-procedure.Additionally,in obese patients or those with severe cardiopulmonary disease,the safety and efficacy of NIVATS are reduced due to inadequate respiratory function.

Key words: non-intubated surgery；video-assisted thoracoscopic surgery；non-small cell lung cancer