Abstract: Objective To compare the efficacy and safety of laparoscopic transabdominal preperitoneal mesh hernia repair (TAPP) and tension-free hernia repair (TFHR) in the treatment of inguinal hernia.Methods From January 2021 to June 2023,85 patients with inguinal hernia were treated in our hospital.They were grouped into TAPP group (n=42,with TAPP) and TFHR group (n=43,with open TFHR) based on the different surgical procedures.The surgical indicators,postoperative pain,serum testosterone levels of male,incidence of postoperative complications,and recurrence rate were compared between two groups.Results Intraoperative blood loss,postoperative exhaust time,and hospital stay in the TAPP group were lower than those in the TFHR group (P<0.05);there was a difference in postoperative numerical rating scale (NRS) scores between two groups (P<0.05),postoperative NRS scores in each group gradually decreased over time (P<0.05),and there was an interaction among groups and time (P<0.05),among them,TAPP group had lower scores than TFHR group at 12,24,and 48 hours after surgery (P<0.05);one month after surgery,there were no difference in serum testosterone levels between the two groups compared before surgery(P>0.05),and there was no difference between the two groups(P>0.05);the incidence of postoperative complications in the TAPP group was lower than that in the TFHR group (4.76% vs 18.60%) (P<0.05);there was no recurrence within 6 months after surgery in both groups.Conclusion The application of TAPP and open TFHR in the treatment of inguinal hernia has good results,and there is no influence on testicular function.However,compared to open TFHR,TAPP has lower intraoperative blood loss,lower postoperative pain and complications,and shorter recovery time.

Key words: preperitoneal mesh hernia repair surgery;tension-free hernia repair surgery;inguinal hernia;pain;complications