Abstract: Objective    To investigate the feasibility of placing single chest tube drainage after total thoracoscopic lobectomy in patients with NSCLC greater than 5cm in diameter. Methods Take a prospective controlled study,selected 120 patients with NSCLC greater than 5cm in diameter who underwent thoracoscopic lobectomy in our hospital.According to the order of hospitalization,then check the random number table into two groups:sixty patients in the control group received double chest tube drainage after operation,the observation group consisted of 60 patients and a single chest tube drainage was placed after the operation.Comparing the two groups of chest drainage,chest drainage time,number of chest punctures after extubation,postoperative hospital stay,visual analogue scale/score(VAS) scores,lung expansion on the 1st and 30th postoperative,reintubation rate,incision complication rate,chest infection rate,pleural effusion rate,and postoperative mortality at 30 days after operation on the 1st and 3rd postoperative day.Results  There were no significant differences in chest drainage,chest drainage time and chest puncture drainage after extubation(P>0.05).The postoperative hospital stay(5.12±0.24)d in the observation group was significantly shorter than that in the control group(5.73±0.57)d,and the difference was statistically significant(P<0.05).The VAS scores of the observation group on the 1st and 30th day after surgery were(3.96±0.07) points and(1.27±0.02) points,respectively,and the control group were(4.51±0.04) points and(1.69±0.02) points,respectively.Tthe VAS scores of the two groups on the 1st and 30th day after operation were statistically significant(P<0.05).There was no significant difference in lung dilatation between the two groups on the 1st and 3rd postoperative(P>0.05).In the observation group,the rate of reintubation was 0,the incidence of incision complications was 3.33%,the rate of chest infection was 1.67%,the rate of pleural effusion was 1.67%,and the mortality rate was 0 after 30 days.The control group was 0,6.67%,3.33%,0,0,respectively.There was no significant difference in the rate of reintubation and related complications between the two groups(P>0.05).〖WTHZ〗Conclusion〖WTBZ〗〓It is feasible to perform single chest tube drainage after thoracoscopic lobectomy in patients with NSCLC greater than 5cm in diameter,drainage effect and safety should be worthy of recognition.Compared with double thoracic drainage,it is superior in reducing postoperative pain.

Key words: nonsmall cell lung cancer, total thoracoscopic lobectomy, single chest tube, double chest tube, drainage