Abstract: Objective   To compare the treatment outcome in patients with acute proximal deep vein thrombosis（DVT）between the two groups，whether pharmacomechanical thrombectomy（PMT）is suitable for patients with trauma for its’ safety and efficacy.Method  45 patients underwent AngioJet rheolytic thrombectomy with/without conjunctive stent implantation or catheterdirected thrombolysis（CDT）and staged stenting were divided into the control group and trauma group.Comparing the complications between two groups，and the risk of postthrombotic syndrome（PTS）was evaluated according to the Villalta scale.A venogram was performed to assess patency follow to 1 year.Results  The CDT time of the control group[（2.23±0.60）d] was noted longer compared with that [（1.60±0.52）d] in the trauma group（P<0.05）.There was no difference of postoperative complication between the two groups（P>0.05），but 2 patients had new PE in the control group after procedure.Comparing the both group with immediate（24 hour）clinical improvement（70.83% vs 76.19%），preoperative VRI scores [（12.71±1.73）vs（12.52±1.33）]，postoperative VRI scores[（2.71±2.29）vs（3.14±1.56）]，Villalta score at one year[（2.39±1.31）vs（2.90±1.55）]，and the primary patency rate at 1 year （83.33% vs 95.24%） reveal no statistical differences（P>0.05）.Conclusion  PMT maybe a safe and efficient treatment for the DVT patients with trauma as contraindication of CDT.

Key words: pharmacomechanical thrombectomy, deep vein thrombosis, trauma, catheterdirected thrombolysis