Abstract: Objective To investigate the effect of through frontal keyhole approach neuroendoscopic surgery of basal ganglia hemorrhage on nerve conduction tract and prognosis.Methods 56 patients with hypertensive basal ganglia hemorrhage treated in our department from October 2017 to October 2023 were selected and divided into observation group and control group.Among them,28 patients in the control group underwent microscopic surgery through temporal cortex approach,while 28 patients in the observation group underwent endoscopic surgery through frontal keyhole approach.Fractional anisotropy and activities of daily living were compared between the two groups after operation.Results The proportion of FA Ⅰ grade in observation group was 88.9% and 70.0% in GCSⅠ grade and GCSⅡ grade patients,respectively,while in control group it was 75.0% and 41.7%.The proportion of ADL Ⅰ and Ⅱ grade in observation group was 94.4% and 70.0% in GCSⅠ grade and GCSⅡ grade patients,respectively,whereas in control group it was 81.3% and 41.7%.The integrity of the corticospinal tract and activities of daily living in observation group were better than those in control group,with statistical significance(P<0.05).Conclusion The surgery of hypertensive basal ganglia hemorrhage with neuroendoscopy through frontal keyhole approach has little influence on nerve conduction tract and the prognosis was better than traditional microscopic surgery through temporal cortex approach.

Key words: basal ganglia hemorrhage;neuroendoscopy;diffusion tensor imaging;activities of daily living