Abstract: Objective This article analyzes the clinical efficacy of silverhawk plaque cyclotomy,Drug-coated balloon(DCB)and bare metal stent in the treatment of patients with lower extremity arterial occlusion.Method A total of 101 patients with lower extremity arterial occlusion admitted to our hospital from January 2019 to December 2021 were prospectively selected and divided into group A for silverhawk plaque rotary cutting treatment by randomized controlled method.Group B was treated with domestic paclitaxel DCB + bare metal stent on the basis of group A,and then its clinical indicators,clinical target lesion revascularization rate,ET-1,NO and plasma P-selectin levels were compared.Results The clinical indexes of group B were significantly better than those of group A(P<0.05).The levels of plasma P-selectin and ET-1 in the two groups were significantly decreased at 12 h after treatment(P<0.05).The levels of NO in the two groups were significantly increased at 12 h after treatment(P<0.05),and the levels of plasma P-selectin,ET-1 and NO in group B were significantly better than those in group A(P<0.05).The revascularization rates at 6 months and 12 months after operation in group B were significantly lower than those in group A(P<0.05).Conclusion Application of silverhawk plaque rotary cutting + domestic paclitaxel DCB + bare metal stent combined treatment of lower extremity arterial occlusion of clinical curative effect is remarkable,improve the patient ’s vascular patency rate,ET-1,NO and plasma P-selectin level,improve the ankle brachial index,reduce the target lesion blood flow reconstruction rate,is worth promoting.

Key words: silverhawk atherectomy, domestic paclitaxel DCB, bare metal stent, lower extremity arterial occlusion