Abstract: Objective：To retrospectively analyze the clinical efficacy of ultrasoundguided microwave ablation and percutaneous ethanol injection in the treatment of benign cystic and solid thyroid nodules.Methods：A retrospective analysis of 140 patients with benign cystic and solid thyroid nodules in our hospital was selected.The patients were divided into 2 groups according to different surgical methods,observation group(percutaneous microwave ablation treatment group) 80 cases,control group(percutaneous absolute alcohol injection treatment group) 60 cases.Compared the two groups of treatment methods 1 day postoperative complications,1 day postoperative stress inflammatory response indicators(CRP,IL6),thyroid function indicators(TSH,FT3,FT4),nodule volume reduction rate at 1,3,6,9 and 12 months postoperative followup,cure rate and total effective rate of treatment at 1 year followup.〖WTHZ〗Results〓〖WTBZ〗The incidence of complications in the observation group(8.75%) was lower than that in the control group(35%),respectively(P＜0.05);the observation group and the control group Postoperative CRP and IL6 both increased,but the observation group had a smaller increase,and the stress inflammatory response was lighter than that of the control group(P<0.05).The incidence of hypothyroidism in the observation group(6.25%) was lower than that of the control group(23.33%) one day after surgery(P<0.05).At 1,3,6,9 and 12 months postoperative followup,the reduction rate of nodule volume in the observation group was greater than that in the control group(P<0.05).The cure rate(72.50%) and total effective rate of treatment(90%) in the observation group during the 1year followup were higher than those in the control group(20.00%) and total effective rate(68.33%),with statistically significant difference(P<0.05).Conclusion：Ultrasoundguided percutaneous microwave ablation is currently a minimally invasive method for the treatment of benign solidcystic thyroid nodules with less damage and safety.

Key words: benign solid cystic thyroid nodules, microwaveablation, percutaneousethanol injection, ultrasoundguided