Abstract: The prevalence of gastroesophageal reflux disease has gradually increased over the past few decades,according to the current research,we know that its related factors are various.Remarkablely,obesity is considered to be one of its important influencing factors.Facing the current increasing incidence of obesity year by year,it is urgent to solve the problem of obesity and its related complications around the word.Fortunately,with the appearance of bariatric metabolic surgery,this problem has been solved gradually.Because of the advantages of high efficiency and safety in solving the problem of obesity,bariatric metabolic surgery has been widely used in the world,and a variety of surgical methods have been produced to adapt to different patients.However,laparoscopic sleeve gastrectomy,as the most widely used in current bariatric metabolic surgery,the influence on gastroesophageal reflux disease is still controversial after solving the problem of obesity and its complications in patients.Some articles pointed out that after laparoscopic sleeve gastrectomy,the symptoms of gastroesophageal reflux were relieved in some patients,however,some articles pointed out that the symptoms of gastroesophageal reflux in a considerable number of patients were significantly aggravated.This paper reviews the relationship between obesity and gastroesophageal reflux diease,the influence of laparoscopic sleeve gastrectomy on gastroesophageal reflux in obese patients,and the changes of gastroesophageal dynamics in patients after laparoscopic sleeve gastrectomy,and then further discusses the significance of highresolution esophageal manometry in the diagnosis of postoperative gastroesophageal reflux diease.

Key words: gastroesophageal reflux disease, laparoscopic sleeve gastrectomy, high resolution esophageal manometry