Abstract: Objective To explore the risk factors related to the development and progression of lumbar degenerative spondylolisthesis（LDS）.Methods A total of 71 patients with LDS or degenerative spinal stenosis（DSS）were retrospectively.Thirty-six patients with LDS（group LDS） and 35 patients with DSS（group DSS）were enrolled.Spinopelvic parameters including pelvic incidence（PI），pelvic tilt（PT），sacral slope（SS），lumbar lordosis（LL），thoracic kyphosis（TK），regional lumbopelvic lordosis angles（PR-LI，PR-L2，PR-L3，PR-L4，PR-L5），pelvic morphology（PR-S1），lumbar 4 slope（L4S）and lumbar 5 slope（L5S）were assessed on whole spine lateral radiographs in a standing position.All the parameters from LDS will compared with those of DSS and normal population respectively，Student’s t-test was used to compare each parameter among the LDS，DSS and normal population.Results PI [（57.67±11.78）°]，SS [（37.83±9.17）°] and LL [（54.65±11.45）°] in group LDS were significantly greater than those of group DSS [（44.47±8.75）°，（28.18±9.02）°，（38.97±15.59）°] and normal reference value [（44.75±9.01）°，（33.57±7.64）°，（48.75±10.03）°]（P<0.05）.L4S [（8.18±9.98）°] and L5S [（19.96±8.33）°] in group LDS were greater than the group DSS[（3.32±7.95）°，（10.87±8.02）°]（P<0.05）.The PR-L4 [（57.63±13.44）°]，PR-L5 [（45.76±10.92）°] and PR-S1 [（27.91±10.41）°] in group LDS were significantly smaller than those of group DSS [（65.48±10.70）°，（56.33±9.15）°，（38.63±7.29）°]（P<0.05）.Conclusion Greater PI may lead to the development and progression of lumbar degenerative spondylolisthesis.L5S is a parameter that can be used to predict the risk of LDS.The lower regional lumbopelvic lordosis angles in LDS were smaller than those of DSS.

Key words: lumbar degenerative spondylolisthesis, degenerative spinal stenosis, sagittal parameters of the spine and pelvis, sagittal balance