Abstract:   Objective  To analyzethe value and curative effect of hand assisted laparoscopy in patients with obesity and colorectal cancer.Methods  90 patients with obesity and colorectal cancer admitted in our hospital,they were divided into observation group and control group according to random number method and 45 patients in each group.The observation group were taken HALS surgery,the control group were taken open surgery.The operation conditions,postoperative condition and stress response of the two groups were compared.Results  There was no significant difference in operation time,number of lymph node dissection between the two groups(P>0.05).The anesthesia time,blood loss and incision length  in the observation group were significantly less than those in the control group(P<0.05).Postoperative body temperature recovery time,anal exhaust time,ambulation time,eating time,hospitalization time in the observation group was significantly shorter than the control group(P<0.05).Before operation,there was no significant difference between the two groups in the levels of interleukin6(IL6),CRP,cortisol and adrenocorticotropic hormone(ACTH)(P>0.05),after two days of operation,the levels of IL6,CRP,cortisol,interleukin6,Creactive protein,cortisol and adrenocorticotrophic hormone in patients with ACTH were significantly higher than those before operation(P<0.5).The level of observation group was significantly lower than that of control group(P<0.05).There was no significant difference in postoperative analgesia between the two groups(P>0.05).The complication rate in the observation group was significantly lower than that in the control group(P<0.05). Conclusion  HALS surgery in patients with obesity and colorectal cancer can reduce the amount of intraoperative bleeding and reduce the degree of involvement,is conducive to the recovery of patients as soon as possible,and reduce the incidence of complications.
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