临床外科杂志 ›› 2025, Vol. 33 ›› Issue (12): 1255-1258.doi: 10.3969/j.issn.1005-6483.20251078

• 专家笔谈 • 上一篇    下一篇

克罗恩病术后营养支持治疗

吴旻娜 朱维铭   

  1. 210029 江苏南京,江苏省中医院 南京中医药大学附属医院炎症性肠病诊疗中心
  • 收稿日期:2025-11-13 出版日期:2025-12-20 发布日期:2025-12-20
  • 通讯作者: 朱维铭,E-mail:yfy135@njucm.edu.cn

Postoperative nutritional management of Crohn's Disease

WU Minna,ZHU Weiming   

  1. Inflammatory Bowel Disease Diagnosis and Treatment Center,Jiangsu Province Hospital of Chinese Medicine,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China
  • Received:2025-11-13 Online:2026-01-22 Published:2025-12-20

摘要: 克罗恩病(CD)是一种慢性、复发性炎症性肠病,尽管内科治疗不断进步,仍有部分病人需外科手术干预。术后营养治疗对促进康复、预防并发症和降低复发风险至关重要。本文系统探讨了CD术后营养支持治疗的四大策略:术后早期肠内营养(EN)的启动与实施,与生物制剂的桥接治疗,补充性肠内营养的应用,回肠切除术后贫血和微量营养素缺乏的防治。通过早期EN促进肠道功能恢复,结合生物制剂预防复发,辅以长期营养支持,并对贫血及微量营养素缺乏进行系统性的监测、预防与治疗,构建了CD术后营养管理的综合策略,旨在改善病人远期预后,提升生活质量。

关键词: 克罗恩病; 术后营养管理; 肠内营养; 生物制剂; 贫血

Abstract: Crohn's disease(CD) is a chronic,relapsing inflammatory bowel disease.Despite continuous advances in medical therapy,a subset of patients still requires surgical intervention.Postoperative nutritional management is crucial for promoting recovery,preventing complications,and reducing the risk of recurrence.This article systematically delineates four pivotal strategies for postoperative nutritional management in CD:the initiation and implementation of early postoperative enteral nutrition(EN),bridging therapy with biologics,the application of Supplemental Enteral Nutrition(SEN),the management of anemia and trace element deficiency following ileal resection.By integrating early EN to restore intestinal function,combining it with biologics to prevent recurrence,and supplementing with long-term nutritional support alongside systematic monitoring,prevention,and treatment of anemia and trace element deficiencies,a comprehensive strategy for postoperative nutritional management in CD is established.This approach aims to improve long-term patient outcomes and enhance quality of life.

Key words: Crohn's disease; postoperative nutritional management; enteral nutrition; biologics; anemia

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