临床外科杂志 ›› 2025, Vol. 33 ›› Issue (12): 1250-1254.doi: 10.3969/j.issn.1005-6483.20251062

• 专家笔谈 • 上一篇    下一篇

胰腺癌病人全程营养管理的临床策略与进展

王艺睿 吴河水 周颖珂   

  1. 430022 湖北武汉,华中科技大学同济医学院附属协和医院胰腺外科
  • 收稿日期:2025-11-09 出版日期:2025-12-20 发布日期:2025-12-20
  • 通讯作者: 吴河水,Emai:heshuiwu@hust.edu.cn;周颖珂,Email:zykwhuh@hust.edu.cn
  • 基金资助:
    国家自然科学基金面上项目(82573059、82573316)

Clinical strategies and progress of whole-course nutritional management for pancreatic cancer patients

WANG Yirui,WU Heshui,ZHOU Yingke   

  1. Department of Pancreatic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China
  • Received:2025-11-09 Online:2026-01-22 Published:2025-12-20

摘要: 胰腺癌病人普遍存在营养不良,严重影响治疗耐受性和预后。营养管理应从诊断开始,贯穿术前、术后及长期随访全过程。关键措施包括早期营养筛查与评估,合理有效的营养补充策略;同时重视胰腺外分泌功能不全的识别与胰酶替代治疗。通过个体化、动态调整的营养干预,结合多学科协作和随访,有望改善病人营养状况、治疗耐受性及生存质量。

关键词: 胰腺癌; 全程营养管理; 围术期管理; 营养治疗

Abstract: Malnutrition is highly prevalent in patients with pancreatic cancer,substantially compromising treatment tolerance and clinical outcomes.Nutritional management should commence upon diagnosis and be maintained continuously throughout the preoperative,postoperative,and long-term follow-up phases.Core components include early nutritional screening and assessment,preferential utilization of enteral nutrition, as well as reasonable and effective nutritional supplementation strategy.At the same time, attention should be paid to the identification of exocrine pancreatic insufficiency and pancreatic enzyme replacement therapy.Through personalized nutritional interventions with dynamic adjustments,integrated with multidisciplinary collaboration and longitudinal follow-up,significant improvements in nutritional status,treatment adherence,and quality of life can be achieved.

Key words: pancreatic cancer; full-process nutrition management; perioperative management; nutritional therapy

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