临床外科杂志 ›› 2020, Vol. 28 ›› Issue (11): 1094-1096.doi: 10.3969/j.issn.1005-6483.2020.11.030

• 综述与讲座 • 上一篇    下一篇

肥胖与高尿酸血症相关性及肥胖合并高尿酸血症的外科治疗进展

  

  1. 乌鲁木齐,新疆医科大学研究生学院
  • 出版日期:2020-11-20 发布日期:2020-11-20

The relationship between obesity and hyperuricemia and the surgical treatment of obesity with hyperuricemia

  • Online:2020-11-20 Published:2020-11-20

摘要: 超重及肥胖的人口数量显著增加,增加了慢性疾病发生的可能性。肥胖与高尿酸血症发病有关且肥胖是高尿酸血症的危险因素之一。高尿酸血症是症状性痛风的主要危险因素,可导致包括痛风、肾损害、关节炎在内的多种疾病。肥胖合并高尿酸血症的机制复杂。减重代谢手术治疗肥胖合并高尿酸血症,安全、有效。本文对肥胖与高尿酸血症的相关性机制研究及其外科治疗进展做一综述。

关键词: 肥胖, 高尿酸血症, 黄嘌呤氧化酶, 腹腔镜袖状胃切除术

Abstract: In recent years,the number of overweight and obese people in China has increased significantly,which will increases the possibility of a series of chronic diseases.Domestic and foreign scholars have reported that obesity is related to the onset of hyperuricemia and obesity is one of the risk factors for hyperuricemia.Hyperuricemia is a major risk factor for symptomatic gout,which can lead to a variety of diseases,including gout,kidney damage,and arthritis.The mechanism of hyperuricemia in obese patients is very complicated.In addition,more and more clinicians advocate weight loss metabolic surgery for the treatment of obesity combined with hyperuricemia as a safe and effective treatment.In this paper,the mechanism of correlation between obesity and hyperuricemia and the progress of surgical treatment were reviewed for clinical reference.

Key words: obesity, hyperuricemia, xanthine oxidase, laparoscopic sleeve gastrectomy

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