脂联素在三阴性乳腺癌发生发展中的作用及机制研究进展

doi:10.3969/j.issn.1005-6483.20260079

JOURNAL OF CLINICAL SURGERY ›› 2026, Vol. 34 ›› Issue (3): 351-354.doi: 10.3969/j.issn.1005-6483.20260079

Research progress on the role and mechanisms of adiponectin in the occurrence and development of triple-negative breast cancer

MA Manqi,ZHANG Lehong,CHEN Jiale,LING Zijun,GAO Zhenjian,HUANG Qianyu,ZHANG Zicheng,LI Mupeng,ZHU Yilin,WANG Saifeng,LIU Minfeng

Online:2026-03-20 Published:2026-05-08

Abstract

Abstract: Department of Breast Surgery,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China

Key words: Decreased adiponectin levels have been associated with an increased risk of breast cancer and poor prognosis.However,the underlying mechanisms of adiponectin in breast cancer,particularly in triple-negative breast cancer,have not been systematically elucidated.This review summarizes the epidemiological evidence linking adiponectin to breast cancer risk and highlights recent advances in the regulatory roles of adiponectin in TNBC,including tumor metastasis,metabolic reprogramming,and the tumor immune microenvironment.The aim of this review is to explore the potential mechanisms by which adiponectin participates in the development and progression of breast cancer and to provide a basis for future studies on metabolism-immune targeted therapeutic strategies.

MA Manqi,ZHANG Lehong,CHEN Jiale,LING Zijun,GAO Zhenjian,HUANG Qianyu,ZHANG Zicheng,LI Mupeng,ZHU Yilin,WANG Saifeng,LIU Minfeng. Research progress on the role and mechanisms of adiponectin in the occurrence and development of triple-negative breast cancer[J].JOURNAL OF CLINICAL SURGERY, 2026, 34(3): 351-354.

References

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed

Comments

Recommended 10

[1]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 737 .
[2]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 744 .
[3]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 753 .
[4]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 777 .
[5]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 802 .
[6]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 785 .
[7]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 807 .
[8]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(10): 808 .
[9]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(11): 809 .
[10]	. [J]. JOURNAL OF CLINICAL SURGERY, 2016, 24(11): 839 .

Research progress on the role and mechanisms of adiponectin in the occurrence and development of triple-negative breast cancer

PDF (PC)

PDF (Mobile)

Abstract

Cite this article

share this article

References

Related Articles 0

Metrics

Comments

Recommended 10