Abstract: Objective To study the change of common bile duct pressure after laparoscopic common bile duct exploration in patients with common bile duct stones.Methods Clinical data of 17 patients with common bile duct stones treated in our hospital from January 2022 to December 2022 were collected. All patients underwent laparoscopic common bile duct exploration and common bile duct pressure measurement. The patients were followed up for 8 weeks after operation, and the common bile duct pressure was measured by indwelling T tube at 2, 3, 4 and 8 weeks.Results Among the 17 patients, 1 patient showed persistent high common bile duct pressure due to residual common bile duct stones. In the remaining 16 patients, there were no significant difference between the initial common bile duct pressure (19.7 cm H₂O) and the common bile duct pressure at postoperative (17.0 cm H₂O) and week 1 (15.5 cm H₂O) (P> 0.05). There were significant differences between the initial common bile duct pressure and the common bile duct pressure at week 2 (13.5 cm H₂O), 3 (12.2 cm H_2O), 4 (11.1 cm H₂O) and 8 (10.0 cm H₂O) (P < 0.05).Conclusion Compared to initial common bile duct pressure,the pressure of common bile duct began to decrease significantly from 2 weeks after laparoscopic common bile duct exploration in patients with common bile duct stones.

Key words: common bile duct stones, common bile duct pressure, common bile duct exploration