Abstract: Objective To study the effects of less invasive stabilization system(LISS) plate combined with minimally invasive percutaneous plate osteosynthesis(MIPPO) technique and open reduction and internal fixation on perioperative indexes and postoperative joint function recovery in patients with tibiofibular fractures.
Methods Totally 92 patients with tibiofibular fractures in our hospital between October 2016 and October 2019 were divided into two groups by random number table method,with 46 cases in each group.Observation group was treated with LISS plate combined with MIPPO technique,and control group was given open reduction and internal fixation.The perioperative indexes,stress indicators,joint function and complications were compared between the two groups.
Results The surgical time,incision size,intraoperative blood loss,hospital stay and fracture healing time in observation group were shorter or less than those in control group(P<0.05).On the 1st d and 7th d after surgery,the levels of serum PGE2,Cor and NE in the two groups were significantly increased(P<0.05),and the levels on the 7th d after surgery were significantly lower than those on the 1st d after surgery(P<0.05),and the levels of serum PGE2,Cor and NE in observation group were lower than those in control group on the 1st d after surgery(P<0.05).The excellent and good rates of joint function in the two groups were 82.61% and 63.04% at 3 months after surgery(P<0.05).The excellent and good rates of joint function in the two groups at 12 months after surgery were 93.48% and 86.96% respectively(P>0.05).The incidence rates of complications were 13.04% and 30.43% in the two groups。respectively(P<0.05).
Conclusion LISS plate combined with MIPPO technique has obvious minimally invasive advantages in the treatment of tibiofibular fractures,and it is beneficial to promote fracture healing and joint function recovery and reduce the surgical complications.

Key words: less invasive stabilizing system plate, minimally invasive percutaneous plate osteosynthesis, tibiofibular fractures, perioperative period, joint function