临床外科杂志 ›› 2025, Vol. 33 ›› Issue (12): 1264-1266.doi: 10.3969/j.issn.1005-6483.20251092

• 专家笔谈 • 上一篇    下一篇

功能保存外科时代慢性放射性肠炎围手术期医学营养治疗

李幼生 田涛 黄雨桦   

  1. 200011 上海,上海交通大学医学院附属第九人民医院普通外科
  • 收稿日期:2025-11-18 出版日期:2025-12-20 发布日期:2025-12-20
  • 通讯作者: 李幼生,Email:gisurgery@hotmail.com
  • 基金资助:
    国家自然科学基金资助项目(81900464、82200621)

Perioperative medical nutrition therapy for patients with chronic radiation enteritis in the era of function preservation surgery

LI Yousheng,TIAN Tao,HUANG Yuhua   

  1. Department of General Surgery,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China
  • Received:2025-11-18 Online:2026-01-22 Published:2025-12-20

摘要: 手术已经替代家庭肠外营养(HPN)成为慢性放射性肠炎(CRE)最重要的治疗方式。CRE的外科治疗也从治疗其并发症进阶到以功能保存为首要目标的外科治疗时代。营养不良是影响CRE病人外科治疗预后的重要因素,CRE病人营养不良发生率高,重度营养不良常见,围手术期医学营养治疗(MNT)时间较外科病人围手术期营养治疗指南的推荐时间长,接受肠外营养(PN)(或联合肠内营养)治疗比例高。广泛放射性损伤肠襻切除后成为短肠综合征(SBS)病人需要继续出院后MNT。免疫营养能够抑制CRE病人的过度炎症反应,但对于改善营养状况和促进肠功能恢复尚需要进一步研究。

关键词: 慢性放射性肠炎; 功能保存外科; 医学营养治疗; 营养不良

Abstract: Surgical management of chronic radiation enteritis(CRE) had replaced home parenteral nutrition(HPN) as the most a critical component.The era of function preservation surgery,surgical management of CRE has also advanced from mitigating severe complications to preserving intestinal function.Malnutrition had been shown to be a risk factor for poor perioperative outcomes of CRE patients.The prevalence of malnutrition in CRE patients was higher and severer malnutrition was more common.The patients needed more long-term MNT than guidelines recommendations in surgery and the ratio of parenteral nutrition or combination of enteral nutrition was higher.The short bowel syndrome patients underwent extensive intestinal resection should be considered to continue MNT after discharge.Immunonutrition has the effect of suppressing excessive inflammation,however,its effects in improving nutritional status and enhancing postoperative recovery of gastrointestinal motility need to investigate in qualitative research.

Key words: chronic radiation enteritis; function preservation surgery; medical nutrition therapy; malnutrition

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