临床外科杂志 ›› 2022, Vol. 30 ›› Issue (8): 752-756.doi: 10.3969/j.issn.1005-6483.2022.08.015

• 论著 • 上一篇    下一篇

神经内镜血肿清除术治疗重型脑室出血并铸型的临床研究

  

  1. 453100 河南新乡,新乡医学院第一附属医院神经外科
  • 收稿日期:2022-02-12 接受日期:2022-02-12 出版日期:2022-08-20 发布日期:2022-08-20
  • 基金资助:
    2017新乡医学院第一附属医院青年基金项目(QN-2017-B025)

Clinical study of neuroendoscopic hematoma removal in the treatment of severe intraventricular hemorrhage cast

  1. Department of Neurosurgery,the First Affiliated Hospital of Xinxiang Medical University,Henan,Xinxiang 453100,China
  • Received:2022-02-12 Accepted:2022-02-12 Online:2022-08-20 Published:2022-08-20

摘要: 目的 探讨神经内镜引导下血肿清除术治疗重型脑室出血铸型的临床效果。方法 回顾性分析2018年12月~2021年6月新乡医学院第一附属医院神经外科收治的重型脑室出血并铸型病人40例,按手术方法分为两组,每例20例,分别采用侧脑室外引流(对照组)和神经内镜血肿清除术(内镜组)治疗。根据术前和术后mGS评分对比评估各组血肿清除情况。对比评估术后尿激酶用量、引流管留置时间,再出血、脑积水和颅内感染等并发症的发生率。术后3月评估预后,ADL分级Ⅰ~Ⅲ级为恢复有效。结果 内镜组术前mGS评分24.55±3.00,术后mGS评分14.45±4.72。对照组术前mGS评分24.70±3.71,术后mGS评分20.40±3.70。组术前术后相比较差异有统计学意义(P<0.05)。两组术前mGS评分相比较差异无统计学意义(P>0.05),内镜组术后与对照组术后mGS评分相比较差异有统计学意义(P<0.05)。内镜组术后残余血肿量更少。术后尿激酶用量内镜组为(3.65±3.24)万u,对照组为(10.15±3.26)万u,内镜组应用更少。脑室外引流留置时间内镜组(8.3±1.7)天,对照组(11.6±1.7)天,内镜组留置时间更短。术后并发症发生率内镜组10.0%,对照组35.0%,内镜组发生率更低。术后3个月ADL评分内镜组有效率70.0%(14/20),对照组有效率30.0%(6/20),内镜组预后更好。结论 神经内镜血肿清除术治疗重型脑室出血铸型可早期快速减少血肿的体积,缓解急性梗阻性脑积水,降低并发症发生率及改善预后,安全有效。

关键词: 神经内镜手术, 血肿清除, 侧脑室外引流术, 脑室出血铸型

Abstract: Objective To investigate the clinical effect of neuroendoscope guided hematoma evacuation in the treatment of severe intraventricular hemorrhage cast. Methods 40 patients with severe intraventricular hemorrhage and casting treated in the Department of Neurosurgery of the First Affiliated Hospital of Xinxiang Medical College from December 2018 to June 2021,20 in the control group and 20 in the endoscopy group were retrospectively analyzed.The hematoma clearance of each group was compared and evaluated according to the preoperative and postoperative MGS scores.The dosage of urokinase,the indwelling time of drainage tube,and the incidence of complications such as rebleeding,hydrocephalus and intracranial infection were compared and evaluated.The prognosis was evaluated 3 months after operation.ADL grade Ⅰ - Ⅲ was effective.Results In the endoscopic group,the preoperative MGS score was 24.55±3.00 and the postoperative MGS score was 14.45±4.72.In the control group,the preoperative MGS score was 24.70±3.71 and the postoperative MGS score was 20.40±3.70.The data compared within groups before and after operation was statistically significant( P<0.05).The preoperative MGS score between the two groups was no significant difference.(P>0.05),the postoperative MGS score btween the two groups were statistically significant( P<0.05),and the amount of residual hematoma in the endoscopic group was less.The dosage of urokinase was (3.65±3.24)million U in the endoscopic group and (10.15±3.26)million U in the control group.The retention time of extraventricular drainage was (8.3±1.7)days in the endoscopic group and (11.6±1.7)days in the control group.The incidence of postoperative complications was 10.0% in the endoscopic group and 35.0% in the control group.Three months after operation,the effective rate of ADL score in endoscopic group was 70.0%(14 / 20).The effective rate of the control group was 30.0%(6/20),and the prognosis of the endoscopic group was better.Conclusion Neuroendoscopic hematoma removal in the treatment of severe intraventricular hemorrhage casting can quickly reduce the volume of hematoma,alleviate acute obstructive hydrocephalus,reduce complications and improve prognosis.It is safe and effective.

Key words: neuroendoscopic surgery, hematoma clearance, lateral ventricle drainage, intraventricular hemorrhage cast

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