关键词: 肠内营养支持, 老年胃癌, 营养状态, 肠道菌群, 应激反应

Abstract: Objective To explore the effect of enteral nutrition support on gastrointestinal function,nutritional status and stress inflammatory response with gastric cancer after radical operation.
Methods The 98 patients with gastric cancer who underwent radical gastrectomy in our hospital from January 2017 to January 2020 were randomly divided into observation group(49 cases) and control group(49 cases).The observation group was treated with enteral nutrition support,while the control group was treated with parenteral nutrition support.The exhaust time,bowel sound time,defecation time,preoperative, postoperative 1 day and 7 days after the changes of nutritional status and intestinal flora, and postoperative 1 day and 7 days after the changes of stress response were compared between the two groups.〖WT5”HZ〗Results The exhaust time,bowel sound time and defecation time of the observation group were faster than those of the control group(P<0.05).After postoperative 7 d,the observation group level of ALB and PA was higher control group(P<0.05).After postoperative 7 d,the observation group number of bifidobacteria was more control group,while that in the Enterococcus and Escherichia coli postoperative 7 d was less control group(P<0.05).After postoperative 7 d,the observation group levels of CRP,IL-6 and Cor in the observation group postoperative 7 d were lower control group(P<0.05).
Conclusion Enteral nutrition support has obvious effect with gastric cancer after operation,which can significantly improve the gastrointestinal function,improve the nutritional status of the patients,correct the intestinal flora disorder and reduce the stress response.

Key words: enteral nutrition support, elderly gastric cancer, nutritional status, intestinal flora, stress response