关键词: 婴幼儿, 供者, 肾, 移植

Abstract: Objective：To summariz the outcome of single kidney transplantation（SKT）from infant donors to adult recipients.Methods：From 2014 to 2016，thirtynine adults receiving SKT from deceased small pediatric donors younger than 3 years old were enrolled and analyzed retrospectively.The recipients were divided into infant donor group（≤1 year age，n=9）and young children group（1＜age＜3 years，n=30）.The incidence of complications and delayed graft function（DGF），patient and graft survival outcomes，serum creatinine level（SCr）were recorded and analyzed.Results：All patients recovered without graft loss due to surgical complications.Two patients in infant donor group died of pneumonia in the first 6 months postoperation.In young children group，one patient died of pneumonia，another died of unknown reason.Deathcensored graft survival were 100% in both groups.There were no significant differences in the incidence of DGF（44.4% vs.26.7%，P＞0.05）and the mean SCr at 12month followup [（74.14±18.52）μmol/L vs.（91.46±26.91）μmol/L，P＞0.05）].Moreover，the incidence of proteinuria showed no significant difference（33.3% vs.36.7%，P＞0.05）.Conclusion：SKT from deceased infant donors could be transplanted into adults with moderate graft function and favorable graft survival outcome.Increased incidence of earlyphase proteinuria may be associated with inadequate size of kidney grafts and hyperperfusion injury.

Key words: pediatric, donor, kidney, transplantation