临床外科杂志 ›› 2025, Vol. 33 ›› Issue (4): 365-369.doi: 10.3969/j.issn.1005-6483.20240571

• 论著 • 上一篇    下一篇

基于CT血管造影三维重建技术的股前外侧游离皮瓣移植在足踝慢性骨髓炎伴软组织缺损治疗中的应用效果

温洋,余晓军,兰家平,陈丽媛,李磊   

  1. 629000 四川省遂宁市中心医院创伤骨科(温洋、兰家平、李磊),手显微外科(余晓军) ,医务科(陈丽媛)
  • 收稿日期:2024-04-17 出版日期:2025-04-20 发布日期:2025-04-20
  • 通讯作者: 李磊,Email:187312808@qq.com
  • 基金资助:
    四川省医学会(泰阁)伤口疾病专项科研课题(2022TG12)

Application effect of anterolateral femoral free flap transplantation based on three-dimensional reconstruction in CT angiography in the treatment of chronic osteomyelitis of the foot and ankle complicated with soft tissues defect

WEN Yang,YU Xiaojun,LAN Jiaping,CHEN Liyuan,LI Lei   

  1. Department of Orthopaedic Center,Suining Central Hospital,Sichuan,Suining 629000,China
  • Received:2024-04-17 Online:2025-04-20 Published:2025-04-20

摘要: 目的 分析基于CT血管造影(CTA)三维重建技术的股前外侧游离皮瓣移植在足踝慢性骨髓炎伴软组织缺损中的应用效果。方法 2020年1月~2023年1月收治的足踝慢性骨髓炎伴软组织缺损病人105例,根据术前对穿支血管检查方法不同分为对照组(52例)和观察组(53例)。对照组采用手持多普勒进行股前外侧游离皮瓣移植修复,观察组采用CTA三维重建技术进行股前外侧游离皮瓣移植修复,比较两组炎症因子[C反应蛋白(CRP)、肿瘤坏死因子(TNF)-α、白细胞介素(IL)-6)]、皮瓣修复效果、足踝功能(AOFAS)评分、皮瓣感觉、皮瓣成活率及不良事件发生率。结果 术后14天观察组血清CRP、TNF-α、IL-6水平低于对照组,两组比较差异有统计学意义(P<0.05)。术后6个月观察组皮瓣修复效果优于对照组,皮瓣成活率高于对照组,两组比较差异有统计学意义(100.0%和92.31%)(P<0.05)。术后12个月观察组AOFAS评分和皮瓣感觉评分高于对照组,两组比较差异有统计学意义(P<0.05)。观察组不良事件发生率低于对照组(3.77%和15.38%),两组比较差异有统计学意义(P<0.05)。结论 基于CTA三维重建技术的股前外侧游离皮瓣移植在修复软组织缺损的同时可治愈慢性骨髓炎,降低不良事件发生风险。

关键词: 慢性骨髓炎, 伴软组织缺损, CT血管造影三维重建技术, 股前外侧游离皮瓣移植

Abstract: Objective To analyze the application effect of anterolateral femoral free flap transplantation based on three-dimensional reconstruction in CT angiography in the treatment of chronic osteomyelitis of the foot and ankle complicated with soft tissues defect.Methods A retrospective analysis was conducted on the clinical data of 105 patients with chronic osteomyelitis of the foot and ankle complicated with soft tissues defect who were admitted to Suining Central Hospital in Sichuan Province from January 2020 to January 2023.Patients enrolled were divided into the control group (n=52) and the observation group (n=53) according to different perforating blood vessel examination methods before surgery.The control group underwent anterolateral femoral free flap transplantation based on handheld Doppler ultrasound,while the observation group underwent anterolateral femoral free flap transplantation based on CTA three-dimensional reconstruction technology.Comparison between the groups was made on inflammatory factors (CRP,TNF-α and IL-6),skin flap repair effect,foot and ankle function (AOFAS) score,flap sensation,survival rate of skin flaps,and the incidence of adverse events.Results On day 14 after operation,serum CRP,TNF-α and IL-6 levels in the observation group were lower than those in the control group (P<0.05).Six months after operation,the effect of flap repair in observation group was better than that in control group,and the survival rate of flap was higher than that in control group (100.00% vs 92.31%) (P<0.05).Twelve months after operation,AOFAS score and flap sensation score of the observation group were higher (P<0.05).The incidence of adverse events was lower in the observation group than in the control group (3.77% vs.15.38%) (P<0.05).Conclusion Anterolateral femoral free flap transplantation based on CTA 3D reconstruction technique can repair soft tissue defect and reduce the risk of adverse events while can cure chronic osteomyelitis.

Key words: chronic osteomyelitis, soft tissues defect, three-dimensional reconstruction in CT angiography, anterolateral femoral free flap transplantation

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