术前炎症状态对下肢动脉硬化闭塞症病人支架置入术后再狭窄的预测价值

doi:10.3969/j.issn.1005-6483.2022.01.027

摘要/Abstract

摘要： 目的探讨术前炎症状态对下肢动脉硬化闭塞症病人支架置入术后再狭窄的预测价值。
方法 2018年8月～2019年2月收治下肢动脉硬化闭塞症病人86例，均行支架置入术治疗，入院时收集病人炎症状态指标，术后随访1年，根据支架置入术后是否发生狭窄分为狭窄组和未狭窄组；采用Logistic回归方法分析术前炎症状态与下肢动脉硬化闭塞症病人支架置入术后再狭窄的相关性，绘制受试者工作曲线，分析其预测价值。
结果随访1年后共6例病人出现失访，最终纳入80例病人，根据支架置入术后是否发生狭窄分为狭窄组(32例)和未狭窄组(48例)；Logistic多因素显示中性粒细胞-淋巴细胞比（NLR）(OR=18.412)、血小板-淋巴细胞比（PLR）(OR=1.205)、低密度脂蛋白(OR=16.968)是下肢动脉硬化闭塞症病人支架置入术后再狭窄的危险因素；ROC曲线分析显示，NLR、PLR在预测下肢动脉硬化闭塞症病人支架置入术后再狭窄的AUC均优于低密度脂蛋白。
结论 NLR、PLR、低密度脂蛋白是下肢动脉硬化闭塞症病人支架置入术后再狭窄的危险因数，支架置入术前监测下肢动脉硬化闭塞症病人NLR、PLR、低密度脂蛋白水平对于预防下肢动脉硬化闭塞症病人支架置入术后再狭窄具重要意义。

关键词: 术前炎症状态, 下肢动脉硬化闭塞症, 支架置入术, 再狭窄预测价

Abstract: Objective To investigate the predictive value of preoperative inflammation in patients with lower extremity arteriosclerosis obliterans and restenosis after stent implantation.
Methods A total of 86 patients who were admitted to our department from August 2018 to February 2019 who were planned to undergo stent implantation for lower extremity arteriosclerosis obliterans were selected as the research objects.Inflammatory status indicators of the patients were collected upon admission and followed up for 1 year.According to Whether stenosis occurs after stent implantation is divided into stenosis group and non-stenosis group;Logistic regression equation is used to analyze the correlation between preoperative inflammation and restenosis after stent implantation in patients with lower extremity arteriosclerosis obliterans,and draw receiver operating curve,Analyze its predictive value.
Results A total of 6 patients were lost to follow-up after 1 year of follow-up,and 80 patients were finally included.According to whether stenosis occurred after stent implantation,they were divided into stenosis group(n=32 cases) and non-stenosis group(n=48 cases);Logistic multivariate showed that NLR(OR=18.412),PLR(OR=1.205),and low-density lipoprotein(OR=16.968) were risk factors for restenosis after stent implantation in arteriosclerosis obliteran patients;ROC curve analysis showed that NLR and PLR were The predictive AUC of restenosis after stent implantation in arteriosclerosis obliteran patients is higher than that of low-density lipoprotein.
Conclusion NLR,PLR,and low-density lipoprotein are the risk factors for restenosis after stent implantation in arteriosclerosis obliteran patients.Monitoring the levels of NLR,PLR,and low-density lipoprotein in arteriosclerosis obliteran patients before stent implantation is important for preventing arteriosclerosis obliteran patients after stent implantation.

Key words: preoperative inflammation, extremity arteriosclerosis obliterans, stent implantation, predictive value of restenosis

王胜利郝云玉. 术前炎症状态对下肢动脉硬化闭塞症病人支架置入术后再狭窄的预测价值[J]. 临床外科杂志, 2022, 30(1): 89-91.

WANG Shengli, HAO Yunyu. The value of preoperative inflammation in predicting restenosis after stent implantation in patients with lower extremity arteriosclerosis obliterans[J]. JOURNAL OF CLINICAL SURGERY, 2022, 30(1): 89-91.

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