临床外科杂志 ›› 2019, Vol. 27 ›› Issue (5): 412-415.doi: 10.3969/j.issn.1005-6483.2019.05.017

• 论著 • 上一篇    下一篇

超声引导经皮腹膜后穿刺置管引流前腹腔穿刺引流治疗重症急性胰腺炎的临床价值

  

  1. 武汉大学中南医院超声影像科
  • 出版日期:2019-05-20 发布日期:2019-05-20

Ultrasoundguided percutaneous retroperitoneal catheterization and preperitoneal drainage for the treatment of severe acute pancreatitis

  • Online:2019-05-20 Published:2019-05-20

摘要: 目的:探讨超声引导经皮腹膜后穿刺置管引流前腹腔穿刺引流治疗重症急性胰腺炎的临床效果。方法:重症急性胰腺炎病人98例,采用随机数字表将其分为两组,对照组49例,采用超声引导经皮腹膜后穿刺置管引流术,试验组49例,先行腹腔穿刺引流治疗,而后超声引导经皮腹膜后穿刺置管引流。比较两组病人术后外周血白细胞水平恢复正常所需时间、器官衰竭率、住院时间、治疗前和治疗后(术后7天)膀胱压、APACHEⅡ评分、血栓素A2(TXA2)含量、前列环素(PGI2)含量和临床疗效。结果:试验组和对照组术后术后外周血WBC恢复正常所需时间分别为(22.31±1.96)天和(26.84±2.07)天,器官衰竭率分别为34.69%和57.14%,差异有统计学意义(P<0.05)。治疗后试验组和对照组APACHEⅡ评分分别为(6.94±3.22)和(11.91±3.86),TXA2分别为(146.53±20.61)ng/ml和(218.21±17.94)ng/ml,PGI2分别为(173.54±15.38)ng/ml和(146.47±16.12)ng/ml,两组比较差异有统计学意义(P<0.05);两组病人临床疗效比较,差异有统计学意义(P<0.05)。结论:超声引导经皮腹膜后穿刺置管引流前腹腔穿刺引流治疗重症急性胰腺炎,能够显著改善预后,减少器官系统的衰竭,提高临床疗效。

关键词: 经皮腹膜后穿刺置管引流, 重症急性胰腺炎, 腹腔穿刺引流, 超声引导

Abstract: Objective:To investigate the clinical effect and prognosis with ultrasoundguided percutaneous retroperitoneal catheterization and preperitoneal drainage for the treatment of severe acute pancreatitis.Methods:98 cases of surgical treatment of severe acute pancreatitis patients,using random numbers table patients were divided into control group (after ultrasoundguided percutaneous peritoneal drainage tube) and the experimental group (first abdominal puncture drainage treatment,and then after ultrasoundguided percutaneous peritoneal drainage tube),49 cases in each group.Compared two groups of patients with postoperative peripheral blood leukocyte levels back to normal time,organ failure rate,the length of time needed for the statistical differences,compared two groups of patients before and after the treatment (7 d) postoperative bladder pressure,APACHEⅡ score,content of TXA2 and PGI2 levels of statistical significance,compared two groups of patients after treatment clinical curative effect of statistical significance.Result:The recovery time of WBC in the experimental group [(22.31±1.96)d] was lower than that in the control group [(26.84±2.07)d],and the organ failure rate in the experimental group (34.69%) was lower than that in the control group (57.14%),the differences were statistically significant(P<0.05).After treatment,treatment group patients with APACHEⅡ score(6.94±3.22) was significantly lower than the control group patients(11.91±3.86)(P<0.05);After treatment,TXA2[(146.53±20.61)ng/ml] in the experimental group was significantly lower than that in the control group [(218.21±17.94)ng/ml](P<0.05),and PGI2[(173.54±15.38)ng/ml] in the experimental group was significantly higher than that in the control group[(146.47±16.12)ng/ml].The recovery rate in the experimental group was significantly higher than that in the control group(P<0.05).Conclusion:Ultrasoundguided percutaneous retroperitoneal catheterization and preperitoneal drainage for the treatment of severe acute pancreatitis can significantly improve the prognosis of patients,reduce organ system failure,and improve clinical efficacy.

Key words: percutaneous retroperitoneal catheterization and drainage, severe acute pancreatitis, peritoneal puncture drainage, ultrasonic

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