关键词: 特发性正常压力脑积水, 腰大池腹腔分流, 脑室腹腔分流

Abstract: Objective To compare the efficacy and safety of lumboperitoneal shunt（LPS）and ventriculoperitoneal shunt（VPS）for patients with idiopathic normal pressure hydrocephalus（iNPH）.Methods 96 patients with iNPH were retrospectively analyzed.Twentyeight patients were treated with LPS（goup LPS） and 68 cases treated with VPS（group VPS）.The clinical symptom，modified Rankin Scale（mRS）score and postoperative complications were compared.Results The improvement of symptoms for group LPS and VPS，were as follows：gait disorder was 60.0% versus 63.5%，dementia was 54.2% versus 57.9%，and urinary inconvenience was 44.4% versus 47.7%（all P>0.05），respectively.The improvements of modified Rankin Scale（mRS）for group LPS and VPS were（-0.9±0.5）versus（-1.0±0.9）（P>0.05）.The proportion of patients experienced postoperative complications were no significant difference between group LPS and VPS（17.9% vs.16.2%，P>0.05）.Conclusion The efficacy and safety rates of group LPS are comparable to those of group VPS in the treatment of patients with iNPH，while LPS can avoid cerebral parenchymal hemorrhage caused by ventricular puncture.

Key words: idiopathic normal pressure hydrocephalus, lumboperitoneal shunt, ventriculoperitoneal shunt